Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution
نویسندگان
چکیده
منابع مشابه
Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution
The success of targeted cancer therapy is limited by drug resistance that can result from tumor genetic heterogeneity. The current approach to address resistance typically involves initiating a new treatment after clinical/radiographic disease progression, ultimately resulting in futility in most patients. Towards a potential alternative solution, we developed a novel computational framework th...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/srep44206